At the recent Regional International Society for Burn Injuries (ISBI) Conference in Thessaloniki, Greece, Lieutenant Colonel Professor Steven Jeffreys presented results from a first-in-human clinical study evaluating Medi-Solfen, a novel “spray-and-stay” topical local anaesthetic for wound management.

The study involved 24 adult patients with small-to-medium lacerations, where Medi-Solfen was applied prior to suturing as an alternative to injected local anaesthesia. Medi-Solfen—combining lidocaine, bupivacaine, adrenaline, and cetrimide—enabled pain-free suturing within five minutes of application.

Based on these encouraging results, the team plans to progress to placebo-controlled Phase 2 trials, with expanded indications including military wounds, burns, and leg ulcers. The potential clinical impact is significant: reducing procedural pain, avoiding general anaesthesia for simple wound closure in children, improving the management of painful chronic wounds, and potentially decreasing reliance on opioid analgesia in acute and military settings.

Further clinical evaluation is planned through the Pioneer Wound Healing and Lymphoedema Centres as Medi-Solfen continues its pathway toward broader clinical application.